Benfotiamine (7.5mg) + Folic Acid (0.75mg) + Methylcobalamin (750mcg) + Pregabalin (75mg) + Vitamin B6 (Pyridoxine) (1.5mg)

🩺 Quick Overview

A fixed-dose combination (FDC) medication designed for the comprehensive management of neuropathic pain, particularly diabetic peripheral neuropathy (DPN). It combines the analgesic and anti-hyperalgesic action of pregabalin with neurotropic B vitamins (Benfotiamine, Methylcobalamin, Pyridoxine) and Folic Acid. This combination aims to address both the symptomatic pain and the underlying metabolic and degenerative components of nerve damage. Benfotiamine, a lipid-soluble prodrug of thiamine, is included for its potential to reduce advanced glycation end-products (AGEs) and improve nerve conduction velocity.

Medical Uses

  • Diabetic Peripheral Neuropathy (DPN) - for neuropathic pain relief and management
  • Neuropathic Pain associated with other conditions (e.g., post-herpetic neuralgia, sciatica) - as an adjunct
  • Nutritional deficiency or increased demand of B-complex vitamins in the context of neuropathy

Side Effects

  • Dizziness
  • Somnolence (drowsiness)
  • Dry mouth
  • Peripheral edema (swelling of hands/feet)
  • Blurred vision
  • Weight gain
  • Difficulty concentrating
  • Headache
  • Nausea

💊 Dosage

One tablet twice daily (BD), or as directed by the physician. The dose may be initiated at once daily for tolerability, especially in elderly or renally impaired patients.

🏭 Available Brands

Pregamax Forte Intas Pharmaceuticals Ltd.Nurokind-Gold Mankind Pharma Ltd.Nervijen Forte Eris Lifesciences Ltd.Maxgalin-BF Forte Torrent Pharmaceuticals Ltd.Pregabanyl-MBF Forte Sun Pharmaceutical Industries Ltd.