Ambroxol (20mg/5ml) + Chlorpheniramine Maleate (2mg/5ml) + Dextromethorphan Hydrobromide (10mg/5ml)

🩺 Quick Overview

A fixed-dose combination syrup used for the symptomatic relief of productive and non-productive cough associated with upper respiratory tract infections, bronchitis, and other respiratory conditions. Ambroxol is a mucolytic agent that thins and loosens phlegm, Chlorpheniramine is a first-generation sedating antihistamine that reduces allergic symptoms and rhinorrhea, and Dextromethorphan is a centrally-acting non-opioid antitussive that suppresses the cough reflex.

Medical Uses

  • Symptomatic relief of productive cough associated with acute and chronic bronchopulmonary disorders (e.g., bronchitis, tracheobronchitis)
  • Symptomatic relief of dry, irritating, non-productive cough

Side Effects

  • Drowsiness, sedation
  • Dryness of mouth, nose, and throat
  • Gastrointestinal discomfort, nausea
  • Dizziness, fatigue
  • Headache

💊 Dosage & Administration

Adult Dosage: 10 ml (2 teaspoonfuls) three times a day. Maximum: 30 ml per day.

Instructions: To be taken orally. Use the measuring cup or spoon provided. Can be taken with or without food. For Ambroxol's mucolytic effect, adequate hydration (plenty of water) is recommended.

🏭 Available Brands in India

Ascoril-CF Glenmark Pharmaceuticals Ltd. Kofarest-AM Macleods Pharmaceuticals Ltd. Chericof-AM Cipla Ltd. Tusq-AM Sun Pharmaceutical Industries Ltd. Bro-Zedex AM Dr. Reddy's Laboratories Ltd.

Mechanism of Action

The combination works synergistically: Ambroxol reduces the viscosity of bronchial secretions, facilitating expectoration. Chlorpheniramine antagonizes histamine at H1 receptors, reducing allergic symptoms like sneezing and rhinorrhea. Dextromethorphan elevates the cough threshold by acting on the medullary cough center, suppressing the cough reflex.