Overview
Croup (laryngotracheobronchitis) is a common childhood respiratory condition characterized by a barking cough, stridor, and hoarseness due to inflammation and edema in the subglottic area of the larynx. It primarily affects children between 6 months and 3 years of age, with peak incidence at 2 years.
Epidemiology: Croup accounts for approximately 15% of respiratory tract infections in children and is the most common cause of acute upper airway obstruction in young children, with seasonal peaks in fall and winter.
Causes & Pathophysiology
Viral Etiology:
- Parainfluenza virus: Types 1 and 2 (most common, 75% of cases)
- Other viruses: Influenza A and B, RSV, adenovirus, metapneumovirus, rhinovirus
- Bacterial causes (rare): Bacterial tracheitis, diphtheria
Pathophysiology:
Viral infection of upper respiratory tract → inflammation and edema of larynx, trachea, and bronchi → particularly affects subglottic area (narrowest part of pediatric airway) → airway narrowing → turbulent airflow → characteristic barking cough and stridor.
Anatomical Considerations:
- Children's airways are naturally narrower than adults
- Subglottic area is the narrowest portion in children
- 1 mm of edema can reduce airway cross-sectional area by 60%
- Same amount of edema causes much greater obstruction in children
Types of Croup:
| Type |
Characteristics |
Severity |
| Viral Croup |
Most common, gradual onset, self-limited |
Mild to moderate |
| Spasmodic Croup |
Sudden onset at night, no fever, recurrent |
Mild to moderate |
| Bacterial Tracheitis |
High fever, toxic appearance, purulent secretions |
Severe |
Symptoms & Presentation
Classic Triad:
- Barking cough: Characteristic seal-like or dog-barking sound
- Stridor: High-pitched, musical breathing sound (primarily inspiratory)
- Hoarseness: Due to vocal cord inflammation
Other Symptoms:
- Low-grade fever (usually <39°C/102.2°F)
- Rhinorrhea (runny nose)
- Mild respiratory distress
- Symptoms typically worse at night
- May have preceding URI symptoms (1-3 days)
Clinical Severity Assessment (Westley Croup Score):
| Parameter |
0 points |
1 point |
2 points |
3 points |
5 points |
| Stridor |
None |
With agitation |
At rest |
- |
- |
| Retractions |
None |
Mild |
Moderate |
Severe |
- |
| Air Entry |
Normal |
Mild decrease |
Moderate decrease |
Severe decrease |
- |
| Cyanosis |
None |
With agitation |
At rest |
- |
- |
| Level of Consciousness |
Normal |
Restless |
Lethargic |
- |
- |
Score Interpretation: Mild (0-2), Moderate (3-5), Severe (6-11), Impending Respiratory Failure (≥12)
Diagnosis & Investigations
Clinical Diagnosis:
Primarily based on characteristic history and physical examination. Laboratory and imaging studies are rarely needed.
Physical Examination:
- Assessment of respiratory distress (retractions, nasal flaring)
- Auscultation for stridor (note if inspiratory, expiratory, or biphasic)
- Evaluation of voice and cry quality
- Assessment of hydration status
- Observation of mental status
Ancillary Tests (when indicated):
| Test |
Purpose |
Findings |
| Neck X-ray (AP view) |
Rule out other diagnoses |
Steeple sign (subglottic narrowing) |
| Pulse Oximetry |
Assess oxygenation |
Usually normal until severe disease |
| Viral Testing |
Identify specific virus |
Not routinely needed |
| Blood Gas |
Assess ventilation |
Only in severe respiratory distress |
Differential Diagnosis:
- Epiglottitis (medical emergency)
- Bacterial tracheitis
- Foreign body aspiration
- Retropharyngeal abscess
- Angioedema or anaphylaxis
- Subglottic stenosis
- Diphtheria (in unvaccinated children)
Management & Treatment
Home Management (Mild Cases):
- Cool mist humidifier
- Comfort measures and reassurance
- Adequate hydration
- Antipyretics for fever (acetaminophen or ibuprofen)
- Observation for worsening symptoms
Medical Treatment:
| Treatment |
Indication |
Dosage/Administration |
| Dexamethasone |
All cases of croup |
0.15-0.6 mg/kg PO/IM (single dose) |
| Nebulized Epinephrine |
Moderate to severe croup |
Racemic: 0.5 mL of 2.25% or L-epinephrine: 5 mL of 1:1000 |
| Oxygen |
Hypoxemia (SpO2 <92%) |
Humidified oxygen via face mask or nasal cannula |
| Heliox |
Severe croup not responding to epinephrine |
70:30 helium-oxygen mixture |
Treatment Algorithm:
- Mild croup (score 0-2): Single dose dexamethasone, home care
- Moderate croup (score 3-5): Dexamethasone, consider nebulized epinephrine, observe 2-4 hours
- Severe croup (score 6-11): Dexamethasone, nebulized epinephrine, oxygen, hospital admission
- Impending respiratory failure (score ≥12): ICU admission, consider intubation
Important: Do not examine the throat in a child with suspected epiglottitis, as this may cause complete airway obstruction. Differentiate croup from epiglottitis based on clinical presentation.
Ayurvedic Treatment
Herbal Support (under medical supervision):
- Sitopaladi Churna: With honey for cough (children >1 year)
- Talisadi Churna: For respiratory symptoms and fever
- Vasa (Adhatoda vasica): Natural bronchodilator
- Tulsi (Holy Basil): Antimicrobial and immunomodulatory
- Ginger and Honey: Soothing for throat irritation
Supportive Measures:
- Steam inhalation with eucalyptus (with caution in young children)
- Warm fluids with turmeric and honey
- Gentle chest massage with warm oils
- Proper hydration with warm water
Note: Ayurvedic treatments should complement, not replace, conventional medical care for croup. Severe croup requires immediate medical attention.
Prognosis
Most cases of viral croup are self-limited and resolve completely within 3-7 days. With appropriate treatment, the prognosis is excellent, and serious complications are rare.
Typical Course:
- Days 1-2: URI symptoms (rhinorrhea, mild cough)
- Days 2-4: Peak of croup symptoms (barking cough, stridor)
- Days 4-7: Gradual improvement
- Day 7+: Complete resolution
Recurrence:
Approximately 5% of children experience recurrent croup episodes. These children may have underlying airway hyperreactivity or anatomical variations.
Potential Complications (Rare):
- Secondary bacterial infection
- Pneumonia
- Pulmonary edema
- Respiratory failure
- Cardiac arrest (very rare with proper treatment)
- Dehydration
Prevention & Screening
Preventive Measures:
- Good hand hygiene to prevent viral spread
- Avoid close contact with sick individuals
- Regular cleaning of frequently touched surfaces
- Annual influenza vaccination for eligible children
- Age-appropriate immunizations
- Breastfeeding (protective effect against severe respiratory infections)
- Avoid smoke exposure
No Specific Screening:
Routine screening for croup is not recommended as it is an acute condition. Prevention focuses on reducing viral transmission and maintaining overall respiratory health.
Parent Education:
- Recognize early signs of respiratory distress
- Know when to seek medical care
- Understand home management strategies
- Have emergency contact information readily available
- Learn basic first aid for respiratory emergencies