Cerebroprotein Hydrolysate is a sterile, pyrogen-free, low molecular weight preparation derived from porcine brain tissue through enzymatic hydrolysis. It contains biologically active peptides, amino acids, and neurotrophic factors. In the Indian context, it is widely prescribed as a neuroprotective and neurotrophic agent for various neurological conditions, primarily to support cognitive recovery and neuronal repair. It is considered a neurometabolic cerebroprotector.
Adult: 30mg once daily, administered by deep intramuscular (IM) injection. The standard course is 10-20 injections, which may be repeated after a break of 2-4 weeks based on clinical assessment.
Note: For IM use only. Do not administer intravenously. Use a deep intramuscular injection, preferably in the gluteal region. The powder must be reconstituted strictly with the provided solvent (usually Water for Injection). Use immediately after reconstitution. Do not mix with other injections in the same syringe.
Exerts its effects through a multimodal mechanism. It provides a source of peptides and amino acids that may act as precursors for neurotransmitter synthesis. It is believed to mimic endogenous neurotrophic factors, promoting neuronal survival, synaptogenesis, and repair. It may enhance cerebral glucose uptake and utilization, improve microcirculation, and stabilize neuronal membranes.
Pregnancy: Category C: Animal reproduction studies have not been conducted. It is not known whether it can cause fetal harm. Use only if the potential benefit justifies the potential risk to the fetus. Generally avoided during pregnancy.
Driving: May cause dizziness. Patients should be cautioned about driving or operating machinery if they experience dizziness.
| Antiepileptic Drugs (e.g., Phenytoin, Valproate) | Theoretical risk of reduced seizure threshold; monitor for seizure activity. | Moderate |
| Other Nootropics/Cerebral Activators (e.g., Piracetam, Citicoline) | Additive pharmacological effect; combination is common in practice but may increase risk of side effects like agitation. | Mild |
| Anticoagulants/Antiplatelets (e.g., Warfarin, Aspirin) | No direct pharmacokinetic interaction known. Use with caution as both may be used in stroke patients. | Mild |
Same composition (Cerebroprotein Hydrolysate (30mg)), different brands: