A fixed-dose combination of essential water-soluble and fat-soluble vitamins, along with D-Panthenol (a provitamin of B5), formulated as a nutritional supplement. It is designed to correct and prevent deficiencies, support metabolic functions, enhance skin and mucosal health, and boost immunity. The combination is particularly relevant in the Indian context due to widespread micronutrient deficiencies, vegetarian diets, and limited sun exposure affecting Vitamin D synthesis.
Adult: As per the specific brand's prescribing information. Typically: 1 ml of oral drops/syrup once daily, or as directed by the physician. Often administered after a meal for better absorption of fat-soluble vitamins.
Note: For oral use only. Shake the bottle well before use. Use the measuring dropper/cup provided. Preferably take with or after a meal containing some fat to enhance absorption of Vitamins A and D3. Do not mix with hot beverages (can degrade Vitamin C).
The combination acts synergistically to support fundamental biochemical pathways. Vitamin A is critical for vision (rhodopsin synthesis), cellular differentiation, and immune function. Vitamin D3 regulates calcium-phosphate homeostasis and modulates immune responses. Thiamine is a coenzyme (TPP) in carbohydrate metabolism and nerve conduction. Vitamin C is a potent antioxidant, cofactor for collagen synthesis, and enhances iron absorption. D-Panthenol, a precursor to pantothenic acid (Coenzyme A), is vital for fatty acid metabolism, epithelialization, and wound healing.
Pregnancy: Category A/C (component-dependent). Vitamin A at this dose (1100 IU ~ 330 mcg RAE) is below the recommended daily allowance (770 mcg RAE) for pregnancy and is considered safe. However, excessive Vitamin A (>10,000 IU/day) is teratogenic. This formulation is likely safe, but use only under medical supervision. Vitamin D, B1, C, and D-Panthenol are safe and recommended.
Driving: No effect on driving ability.
| Isotretinoin, Acitretin | Additive risk of Vitamin A toxicity (hypervitaminosis A). | Major |
| Orlistat, Mineral Oil | Reduced absorption of fat-soluble vitamins (A, D). Administer at least 2 hours apart. | Moderate |
| Cholestyramine, Colestipol | Reduced absorption of fat-soluble vitamins (A, D) and possibly others. | Moderate |
| Phenytoin, Phenobarbital | Increased metabolism of Vitamin D, reducing its efficacy. May require dose adjustment. | Moderate |
| Warfarin | High-dose Vitamin A or Vitamin E may potentiate anticoagulant effect. Low dose likely safe, but monitor INR. | Moderate |
| Iron Supplements | Vitamin C enhances non-heme iron absorption. Beneficial interaction. | Minor |
| Levodopa | High-dose Vitamin C may reduce efficacy (theoretical). Low dose unlikely significant. | Minor |
| Fluorouracil, Doxorubicin | D-Panthenol may reduce skin toxicity from these chemotherapeutics (protective). | Minor |
Same composition (Vitamin A (1100IU) + Vitamin D3 (100IU) + Thiamine(Vitamin B1) (5mg) + Vitamin C (15mg/ml) + D-Panthenol (2.5mg)), different brands: