A comprehensive, multi-ingredient antacid and anti-flatulent suspension indicated for the symptomatic relief of hyperacidity, gastroesophageal reflux disease (GERD), and associated dyspepsia. It combines fast-acting and long-acting antacids with a potent topical anesthetic and a defoaming agent for rapid and sustained relief from pain, burning, and bloating.
Adult: 10 ml (2 teaspoonfuls) 3 to 4 times daily, preferably 20-60 minutes after meals and at bedtime, or as directed by the physician. Maximum: 40 ml per day.
Note: Shake the bottle well before use. Measure dose accurately with provided measuring cup/spoon. To be taken orally. May be followed with a small amount of water. Do not take with other medications (maintain a 2-hour gap). For optimal effect, take 20-60 minutes after meals and at bedtime.
1. **Antacids (Aluminium Hydroxide, Magnesium Trisilicate, Magnesium Hydroxide)**: Neutralize gastric hydrochloric acid, raising the intragastric pH. This reduces pepsin activity and provides a physical protective coating (especially Magnesium Trisilicate). 2. **Oxetacaine**: A potent surface anesthetic that blocks sodium channels in neuronal membranes, inhibiting the initiation and conduction of nerve impulses, thereby providing rapid relief from pain and burning sensations in the esophagus and stomach. 3. **Simethicone**: A physiologically inert defoaming agent that reduces the surface tension of gas bubbles, causing them to coalesce and be more easily expelled by belching or passing flatus, relieving bloating and discomfort.
Pregnancy: Category C (US FDA). Use only if clearly needed. Oxetacaine systemic absorption is negligible, but antacids are generally considered low risk for occasional use. Avoid prolonged, high-dose use. Magnesium salts in high doses could theoretically affect uterine contractility. Consult physician.
Driving: Unlikely to affect driving ability. However, if rare side effects like dizziness or headache occur, caution is advised.
| Tetracyclines (Doxycycline, Tetracycline) | Markedly decreased absorption due to chelation by divalent/trivalent cations (Al3+, Mg2+). | Major |
| Fluoroquinolones (Ciprofloxacin, Levofloxacin) | Markedly decreased absorption due to chelation. | Major |
| Iron supplements | Decreased absorption of iron. | Moderate |
| Digoxin | Decreased absorption of digoxin. Also, hypermagnesemia/hypokalemia can potentiate digoxin toxicity. | Moderate |
| Anticoagulants (Warfarin) | Possible altered INR; monitor closely. | Moderate |
| ACE Inhibitors (Captopril, etc.) | Decreased absorption. | Moderate |
| Bisphosphonates (Alendronate) | Severely decreased absorption. | Major |
| Thyroid hormones (Levothyroxine) | Decreased absorption. | Moderate |
| Ketoconazole, Itraconazole | Decreased absorption due to increased gastric pH. | Major |
| Antipsychotics (Phenothiazines), Anticholinergics | Decreased absorption. | Moderate |