Decapeptyl SR (Brand Originator - in other markets; daily formulation not commonly marketed in India)

ℹ️ Why is it prescribed?

Decapeptyl SR (Brand Originator - in other markets; daily formulation not commonly marketed in India) contains Triptorelin (0.5mg/ml). It is primarily used for:

• Advanced Hormone-Dependent Prostate Carcinoma (Palliative treatment)
• Central Precocious Puberty (CPP) in children (as part of specific management protocols)
• Endometriosis (management of pain and reduction of lesions)
• Uterine Fibroids (Leiomyomata) - pre-operative reduction of size and symptoms

Side Effects

• Hot flushes (flashes)
• Increased sweating (hyperhidrosis)
• Headache
• Injection site reactions (pain, erythema, itching, swelling)
• Decreased libido
• Erectile dysfunction (in males)
• Vaginal dryness, dyspareunia (in females)
• Amenorrhea
• Fatigue
• Mood swings, emotional lability
• Initial transient worsening of symptoms (bone pain, urinary issues) due to flare effect

Contraindications

• Hypersensitivity to triptorelin, other GnRH agonists, or any excipients
• Pregnancy (Category X - see special populations)
• Breastfeeding
• Undiagnosed abnormal vaginal bleeding
• Patients with conditions exacerbated by hypoestrogenism (e.g., severe osteoporosis where risk outweighs benefit)