Vitamin C (Ascorbic Acid) is a water-soluble essential vitamin and potent antioxidant. In the Indian context, it is widely used for the prevention and treatment of vitamin C deficiency (scurvy), to support immune function, and to enhance non-heme iron absorption. The 150mg strength is a common prophylactic and therapeutic dose suitable for the Indian population, addressing dietary gaps and increased requirements during stress or illness.
Adult: Prophylactic: 70-150mg daily. Therapeutic (Scurvy): 500mg to 1g daily for at least 2 weeks, followed by prophylactic dose.
Note: Administer orally, preferably with or after meals to reduce gastric irritation. Tablet/Capsule should be swallowed whole with a glass of water. Chewable tablets should be chewed thoroughly. Do not crush sustained-release formulations. Can be taken with iron supplements to enhance absorption.
Vitamin C acts as an essential cofactor for multiple enzymatic reactions, including the biosynthesis of collagen, carnitine, and neurotransmitters (norepinephrine). It is a potent water-soluble antioxidant that scavenges reactive oxygen and nitrogen species, thereby protecting cellular components from oxidative damage. It also regenerates other antioxidants like vitamin E. It enhances immune cell function (neutrophils, lymphocytes) and facilitates dietary iron absorption by reducing ferric iron (Fe3+) to the more absorbable ferrous form (Fe2+).
Pregnancy: Category A (when used in recommended dietary amounts). 150mg daily is safe. Higher doses should be used only if clearly needed. Required for fetal collagen synthesis.
Driving: No effect on ability to drive or operate machinery.
| Oral Iron Supplements (Ferrous sulfate) | Vitamin C enhances iron absorption by maintaining it in ferrous state. | Moderate |
| Aspirin | May increase renal excretion of ascorbic acid and decrease its uptake by leukocytes. | Moderate |
| Fluphenazine, Warfarin | Vitamin C may decrease serum levels/effects of these drugs. | Moderate |
| Aluminum-containing antacids | Vitamin C may increase aluminum absorption, potentially increasing toxicity. | Major |
| Estrogens, Oral Contraceptives | May increase serum vitamin C levels. | Minor |